The Research on a New Feeding Device of Low-Temperature Deposition for Fabricating Tissue Engineering Scaffolds

Low-temperature deposition manufacturing (LDM) has been proven as an effective bone scaffold preparation process, but its further application has been seriously hindered by the existing material over-accumulation problem. In view of the over-accumulation problem of the traditional pneumatic extrusion material feeding way, designed and developed a feeding system based on pneumatic-extrusion and valve-control, which can achieve rapid pressure/relief, Combined with the inflation / deflation time calculation method of fixed volume container for analysis and calculation. A unified data management method of the material feeding device and a regulation scheme of the controller are given. Experimental results show that, by adjusting parameters, the feeding system based on pneumatic-extrusion and valve-control can achieve rapid gas pressure/relief, the flux has been well controlled, the over-accumulation on deposition path at the end has been eliminated, which lead to effective guarantee of scaffold forming quality.