Chemiluminescence Enhancement Effect for the Determination of Acetaminophen with the Catalysis of Manganese Deuteroporphyrin (Mn(III)DP)

It is found thatManganese Deuteroporphyrin (Mn(Ⅲ)DP) can greatly enhance the chemiluminescence intensity of luminol-hydrogen peroxide system in alkaline conditions. Basing on that fact a flow injection chemiluminescence (CL) method has been developed for the determination of acetaminophen. With the...

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Veröffentlicht in:Key engineering materials 2013-09, Vol.575-576, p.249-252
Hauptverfasser: Chao, Ying Jun, Xie, Liang Xiao, Cao, Wei
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Sprache:eng
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Zusammenfassung:It is found thatManganese Deuteroporphyrin (Mn(Ⅲ)DP) can greatly enhance the chemiluminescence intensity of luminol-hydrogen peroxide system in alkaline conditions. Basing on that fact a flow injection chemiluminescence (CL) method has been developed for the determination of acetaminophen. With the peak height as a quantitative parameter applying optimum conditions, the relative CL intensity was linear with acetaminophen concentration in the range of 1.0×10-9~1.0×10-7 g/mL with a detection limit of 2.8×10-10 g/mL. The relative standard deviation (RSD) was 2.7% for 2.0 x10-8 g/mL acetaminophen (n = 11). The proposed method held low detection limit and was successfully applied to determination of acetaminophen in pharmaceutical preparations.
ISSN:1013-9826
1662-9795
1662-9795
DOI:10.4028/www.scientific.net/KEM.575-576.249