Electrospun Antibacterial Chitosan-Based Fibers
Chitosan is non‐toxic, biocompatible, and biodegradable polysaccharide from renewable resources, known to have inherent antibacterial activity, which is mainly due to its polycationic nature. The combining of all assets of chitosan and its derivatives with the unique properties of electrospun nanofi...
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Veröffentlicht in: | Macromolecular bioscience 2013-07, Vol.13 (7), p.860-872 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Chitosan is non‐toxic, biocompatible, and biodegradable polysaccharide from renewable resources, known to have inherent antibacterial activity, which is mainly due to its polycationic nature. The combining of all assets of chitosan and its derivatives with the unique properties of electrospun nanofibrous materials is a powerful strategy to prepare new materials that can find variety of biomedical applications. In this article the most recent studies on different approaches for preparation of antibacterial fibrous materials from chitosan and its derivatives such as electrospinning, coating, and electrospinning‐electrospraying, loading of drugs or bioactive nanoparticles are summarized.
Combining the valuable biological properties of chitosan and its derivatives with the favorable properties of electrospun nanofibrous materials is a promising strategy for the preparation of a new generation of antibacterial materials. This article mainly focuses on different electrospinning approaches proposed for the fabrication of chitosan‐based antibacterial nanofibrous materials. |
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ISSN: | 1616-5187 1616-5195 |
DOI: | 10.1002/mabi.201300058 |