Labeling Studies on the Formation Pathway of Nε-Carboxymethyllysine in Maillard-type Reactions

Labeling Studies on the Formation Pathway of Nε-Carboxymethyllysine in Maillard-type Reactions

: Nε‐carboxymethyllysine (CML) is among the most often studied advanced glycation end products (AGEs) in foods and medicine, and several pathways have been suggested for its formation. Based on the results of model studies using glucose labeled with carbon‐13 in different positions, a new pathway is...

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Veröffentlicht in:Annals of the New York Academy of Sciences 2005-06, Vol.1043 (1), p.59-62
Hauptverfasser: KASPER, MARTINA, SCHIEBERLE, PETER
Format: Artikel
Sprache:eng
Schlagworte:
advanced glycation end products (AGEs)
Age
Autoxidation
Foods
Glucose
Marking
Medicine
Nε-carboxymethyllysine (CML)
Pathways
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Zusammenfassung:: Nε‐carboxymethyllysine (CML) is among the most often studied advanced glycation end products (AGEs) in foods and medicine, and several pathways have been suggested for its formation. Based on the results of model studies using glucose labeled with carbon‐13 in different positions, a new pathway is proposed for CML formation without involving free glyoxal or autoxidation reactions.
ISSN:0077-8923
1749-6632
DOI:10.1196/annals.1333.007