Highly Sensitive Detection of Red Blood Cell Aggregation with Ultrasonic Peak Frequency
A novel technique of detecting the peak frequency of an ultrasonic reflection spectrum was proposed, with the aim of enhancing the sensitivity and accuracy of estimating the aggregation size of red blood cells (RBCs). Peak frequencies for stagnant and running suspensions prepared with monodisperse p...
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Veröffentlicht in: | Japanese Journal of Applied Physics 2013-07, Vol.52 (7), p.07HF18-07HF18-6 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A novel technique of detecting the peak frequency of an ultrasonic reflection spectrum was proposed, with the aim of enhancing the sensitivity and accuracy of estimating the aggregation size of red blood cells (RBCs). Peak frequencies for stagnant and running suspensions prepared with monodisperse particles of graphite and acryl that were used to mimic aggregated RBCs were acquired. As a result, the relationships between particle diameter and peak frequency, which were independent of the material of the particles and flow rate, were obtained. For bidisperse samples, i.e., mixtures of two different sizes of particle samples, quantitative relationships corresponding to changes in the mixing ratio were observed. |
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ISSN: | 0021-4922 1347-4065 |
DOI: | 10.7567/JJAP.52.07HF18 |