Plasma polymerised polyoxazoline thin films for biomedical applications

Poly(2-oxazoline)s are emerging revolutionary biomaterials, exhibiting comparable and even superior properties to well-established counterparts. Overcoming current tedious wet synthesis methods, we report solvent-free and substrate independent, plasma polymerised nanoscale biocompatible polyoxazolin...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2015-03, Vol.51 (20), p.4279-4282
Hauptverfasser:	Ramiasa, M N, Cavallaro, A A, Mierczynska, A, Christo, S N, Gleadle, J M, Hayball, J D, Vasilev, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Biofilms Biomaterials Biomedical materials Cell Adhesion Cell Survival Cells, Cultured Fibroblasts - drug effects Fibroblasts - metabolism Humans Interleukin-6 - metabolism Macrophages - drug effects Oxazoles - chemistry Oxazoles - pharmacology Polyamines - chemistry Polymerization Polyoxazolines Serum Albumin, Bovine - chemistry Surgical implants Thin films Tumor Necrosis Factor-alpha - metabolism
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Beschreibung
Zusammenfassung:	Poly(2-oxazoline)s are emerging revolutionary biomaterials, exhibiting comparable and even superior properties to well-established counterparts. Overcoming current tedious wet synthesis methods, we report solvent-free and substrate independent, plasma polymerised nanoscale biocompatible polyoxazoline coatings capable of controlling protein and cell adhesion, and significantly reducing biofilm build up.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c5cc00260e