Determination of N-nitrosodiethanolamine, NDELA in cosmetic ingredients and products by mixed mode solid phase extraction and UPLC–tandem mass spectrometry with porous graphitic carbon column through systemic sample pre-cleanup procedure
A rapid, sensitive, accurate and specific ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC–MS/MS) method for the detection of N-nitrosodiethanolamine (NDELA), a highly toxic contaminant in cosmetic raw materials and products was developed and validated. Systematized...
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Veröffentlicht in: | Talanta (Oxford) 2015-05, Vol.137, p.109-119 |
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Format: | Artikel |
Sprache: | eng |
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