Serum albumin adsorbed on Au nanoparticles: structural changes over time induced by S-Au interaction

Serum albumin adsorbed on Au nanoparticles: structural changes over time induced by S-Au interaction

We report the evolution of the protein secondary structure of HSA adsorbed on AuNPs over time. This evolution is in agreement with the S-Au interaction time determined by Raman spectroscopy. The results indicate that the changes in the secondary structure of HSA are induced by the S-Au interaction.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2015-02, Vol.51 (17), p.3634-3636
Hauptverfasser: Fu, Cuiping, Yang, Huayan, Wang, Mengmeng, Xiong, Huanming, Yu, Shaoning
Format: Artikel
Sprache:eng
Schlagworte:
Adsorption
Evolution
Gold
Gold - chemistry
Humans
Metal Nanoparticles - chemistry
Models, Molecular
Molecular Structure
Nanoparticles
Particle Size
Proteins
Raman spectroscopy
Serum albumin
Serum Albumin - chemistry
Spectrum Analysis, Raman
Sulfur - chemistry
Surface Properties
Time Factors
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Beschreibung
Zusammenfassung:We report the evolution of the protein secondary structure of HSA adsorbed on AuNPs over time. This evolution is in agreement with the S-Au interaction time determined by Raman spectroscopy. The results indicate that the changes in the secondary structure of HSA are induced by the S-Au interaction.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc08372e