Fate of the benzoylphenyl urea CGA-184699 in the cat flea Ctenocephalides felis

HPLC was used to determine levels of the benzoylphenyl urea. CGA-184699, cat blood, flea faeces and eggs. Rate constants were determined for the decline of CGA-184699 concentration in flea faeces of fleas that fed on both high (696 ng ml-1) and low (305 ng ml-1) host blood concentrations. There were...

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Veröffentlicht in:	Pesticide Science 1992, Vol.35 (2), p.117-123
Hauptverfasser:	Zakson, M, Hink, W.F, MacKichan, J.J
Format:	Artikel
Sprache:	eng
Schlagworte:	benzoylphenylureas Biological and medical sciences blood serum cats Ctenocephalides felis egg hatchability feces Fundamental and applied biological sciences. Psychology insect control Invertebrates larvae Medically important nuisances and vectors, pests of stored products and materials: population survey and control mortality Nuisances ova Pulicidae Siphonaptera
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Zusammenfassung:	HPLC was used to determine levels of the benzoylphenyl urea. CGA-184699, cat blood, flea faeces and eggs. Rate constants were determined for the decline of CGA-184699 concentration in flea faeces of fleas that fed on both high (696 ng ml-1) and low (305 ng ml-1) host blood concentrations. There were strong correlations between the concentration of the drug in the host's blood and in flea eggs, between egg concentration and egg hatch and between the concentration of CGA-184699 in faeces and mortality to larvae feeding upon faeces.
ISSN:	0031-613X 1526-498X 1096-9063
DOI:	10.1002/ps.2780350204