Establishment of monoclonal antibodies against a novel eosinophil-specific cell surface molecule, major facilitator super family domain containing 10

Highlights ► Identification of Mfsd10 as a novel eosinophil-specific cell surface molecule. ► Establishment of anti-mouse Mfsd10 monoclonal antibodies. ► Selective reactivity of the anti-Mfsd10 antibody on eosinophils.

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Bibliographische Detailangaben
Veröffentlicht in:	Immunology letters 2012-09, Vol.147 (1), p.80-84
Hauptverfasser:	Motoi, Yuji, Saeki, Mayumi, Nishimura, Tomoe, Katayama, Kazufumi, Kitamura, Noriko, Ichikawa, Hitoshi, Miyoshi, Hiroyuki, Kaminuma, Osamu, Hiroi, Takachika
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic inflammation Allergy and Immunology Animals Antibodies, Monoclonal - immunology Antibodies, Neutralizing - immunology Antigens - immunology Bronchoalveolar Lavage Fluid - cytology Bronchoalveolar Lavage Fluid - immunology Cluster Analysis Eosinophils Eosinophils - immunology Eosinophils - metabolism Female Gene Expression Gene Expression Profiling Membrane Proteins - genetics Membrane Proteins - immunology Membrane Transport Proteins - genetics Membrane Transport Proteins - immunology Mfsd10 Mice Microarray analysis Monoclonal antibody
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Beschreibung
Zusammenfassung:	Highlights ► Identification of Mfsd10 as a novel eosinophil-specific cell surface molecule. ► Establishment of anti-mouse Mfsd10 monoclonal antibodies. ► Selective reactivity of the anti-Mfsd10 antibody on eosinophils.
ISSN:	0165-2478 1879-0542
DOI:	10.1016/j.imlet.2012.07.001