Peripheral Blood Mononuclear Cells HIV DNA Levels Impact Intermittently on Neurocognition: e0120488

Peripheral Blood Mononuclear Cells HIV DNA Levels Impact Intermittently on Neurocognition: e0120488

Objectives To determine the contribution of peripheral blood mononuclear cells' (PBMCs) HIV DNA levels to HIV-associated dementia (HAD) and non-demented HIV-associated neurocognitive disorders (HAND) in chronically HIV-infected adults with long-term viral suppression on combined antiretroviral...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PloS one 2015-04, Vol.10 (4)
Hauptverfasser: Cysique, Lucette A, Hey-Cunningham, William J, Dermody, Nadene, Chan, Phillip, Brew, Bruce J, Koelsch, Kersten K
Format: Artikel
Sprache:eng
Schlagworte:
Human immunodeficiency virus
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Objectives To determine the contribution of peripheral blood mononuclear cells' (PBMCs) HIV DNA levels to HIV-associated dementia (HAD) and non-demented HIV-associated neurocognitive disorders (HAND) in chronically HIV-infected adults with long-term viral suppression on combined antiretroviral treatment (cART). Methods Eighty adults with chronic HIV infection on cART (>97% with plasma and CSF HIV RNA
ISSN:1932-6203
DOI:10.1371/journal.pone.0120488