Effects of particle uptake, encapsulation, and localization in cancer cells on intracellular applications

Effects of particle uptake, encapsulation, and localization in cancer cells on intracellular applications

Highlights • Endocytosis is affected by cell function, and likely malignancy. • Particles endocytose into cells with reduced cell–cell interactions. • Endocytosed particles may become unencapsulated by membranes with time. • Endocytosis can safely be used to internalize particles for tracking....

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Veröffentlicht in:Medical engineering & physics 2015-05, Vol.37 (5), p.478-483
Hauptverfasser: Gal, N, Massalha, S, Samuelly-Nafta, O, Weihs, D
Format: Artikel
Sprache:eng
Schlagworte:
Breast cancer cells
Breast Neoplasms - metabolism
Cell Line
Cell Line, Tumor
Cytoplasm - metabolism
Endocytosis - physiology
Endosomes - metabolism
Epithelial Cells - metabolism
Flow Cytometry
Humans
Intracellular mechanics
Microencapsulation
Microscopy, Confocal
Motion
Nanoparticles
Nanoparticles - administration & dosage
Particle tracking in living cells
Radiology
Time Factors
Time-dependent endocytosis
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Beschreibung
Zusammenfassung:Highlights • Endocytosis is affected by cell function, and likely malignancy. • Particles endocytose into cells with reduced cell–cell interactions. • Endocytosed particles may become unencapsulated by membranes with time. • Endocytosis can safely be used to internalize particles for tracking.
ISSN:1350-4533
1873-4030
DOI:10.1016/j.medengphy.2015.03.003