Prehospital fluid management of abdominal organ trauma patients—a matched pair analysis
Purpose Severe bleeding after trauma frequently leads to a poor outcome. Prehospital fluid replacement therapy is considered an important primary treatment option. We conducted a retrospective matched pair analysis to assess the influence of prehospital fluid replacement volume on the clinical cours...
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Veröffentlicht in: | Langenbeck's archives of surgery 2015-04, Vol.400 (3), p.371-379 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Purpose
Severe bleeding after trauma frequently leads to a poor outcome. Prehospital fluid replacement therapy is considered an important primary treatment option. We conducted a retrospective matched pair analysis to assess the influence of prehospital fluid replacement volume on the clinical course of patients with solid abdominal organ trauma.
Methods
Data were analyzed from 51,425 patients in TraumaRegister DGU® of the German Trauma Society. Inclusion criteria were as follows: injury severity score ≥16 points, primary admission, age ≥16 years, no isolated brain injury, transfusion of at least one unit of packed red blood cells (pRBCs), and systolic blood pressure ≥20 mmHg at the accident site. The patients were divided into “low-volume” (0–1000 ml) and “high-volume” (≥1500 ml) groups according to the matched pair criteria. In each group, 68 patients met the inclusion criteria.
Results
Higher volume in fluid replacement was associated with increased need for transfusion (pRBCs: low-volume: 7.71 units, high-volume: 9.16 units;
p
= 0.074) and with by trend reduced clotting ability (prothrombin time: low-volume: 71.47 %, high-volume: 66.47 %;
p
= 0.27). The percentage of patients in shock (systolic blood pressure |
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ISSN: | 1435-2443 1435-2451 |
DOI: | 10.1007/s00423-015-1274-2 |