Complete sequence of a bla(KPC)-harboring cointegrate plasmid isolated from Escherichia coli
Horizontal transfer of bla(KPC)-harboring plasmids contributes significantly to the inter- and intraspecies spread of Klebsiella pneumoniae carbapenemase (KPC). Here we report the complete nucleotide sequence of a bla(KPC)-harboring IncFIA plasmid, pBK32533, from Escherichia coli. pBK32533 is a coin...
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Veröffentlicht in: | Antimicrobial agents and chemotherapy 2015-05, Vol.59 (5), p.2956-2959 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Horizontal transfer of bla(KPC)-harboring plasmids contributes significantly to the inter- and intraspecies spread of Klebsiella pneumoniae carbapenemase (KPC). Here we report the complete nucleotide sequence of a bla(KPC)-harboring IncFIA plasmid, pBK32533, from Escherichia coli. pBK32533 is a cointegrate plasmid comprising of a 72-kb sequence identical to that of the nonconjugative pBK30661 plasmid plus an additional 170-kb element that harbors the genes for plasmid transfer. pBK32533 demonstrates how bla(KPC) can be spread from a nonconjugative plasmid through cointegration. |
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ISSN: | 1098-6596 |
DOI: | 10.1128/AAC.00041-15 |