Primary and secondary bone lymphomas

Highlights • Three clinical forms of bone lymphoma exist: the primary, the polyostotic and the secondary bone lymphoma. • Level of evidence supporting therapeutic decisions in these rare tumors is low, and prospective trials appear unrealistic. • This review is based on the analysis of the largest a...

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Veröffentlicht in:Cancer treatment reviews 2015-03, Vol.41 (3), p.235-246
Hauptverfasser: Messina, Carlo, Christie, David, Zucca, Emanuele, Gospodarowicz, Mary, Ferreri, Andrés J.M
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container_end_page 246
container_issue 3
container_start_page 235
container_title Cancer treatment reviews
container_volume 41
creator Messina, Carlo
Christie, David
Zucca, Emanuele
Gospodarowicz, Mary
Ferreri, Andrés J.M
description Highlights • Three clinical forms of bone lymphoma exist: the primary, the polyostotic and the secondary bone lymphoma. • Level of evidence supporting therapeutic decisions in these rare tumors is low, and prospective trials appear unrealistic. • This review is based on the analysis of the largest available database of bone lymphomas and of relevant literature. • We provide recommendations for diagnosis, staging and treatment of patients with bone lymphoma in everyday practice. • Special conditions like pathological fractures, indolent lymphomas and central nervous system prophylaxis are also discussed.
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subjects Bone Neoplasms - diagnosis
Bone Neoplasms - pathology
Bone Neoplasms - secondary
Bone Neoplasms - therapy
Diffuse large B-cell lymphoma
Extranodal lymphoma
Hematology, Oncology and Palliative Medicine
Humans
Lymphoma - diagnosis
Lymphoma - pathology
Lymphoma - therapy
Osteolymphoma
Polyostotic lymphoma
Primary bone lymphoma
title Primary and secondary bone lymphomas
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