Life-threatening acute lung injury after gamma butyrolactone ingestion

We describe a case of a 44-year-old woman with a borderline personality disorder and chronic gamma- butyrolactone (GBL) use who presented with progressive dyspnoea and an altered mental status. A high anion gap metabolic acidosis and acute lung injury was diagnosed. We hypothesise this was caused by...

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Veröffentlicht in:	Netherlands journal of medicine 2015-03, Vol.73 (3), p.133-135
Hauptverfasser:	van Gerwen, M, Scheper, H, Touw, D J, van Nieuwkoop, C
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Butyrolactone - poisoning Acute Lung Injury - chemically induced Acute Lung Injury - diagnostic imaging Adult Deglutition Female Humans Solvents - poisoning Tomography, X-Ray Computed
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Zusammenfassung:	We describe a case of a 44-year-old woman with a borderline personality disorder and chronic gamma- butyrolactone (GBL) use who presented with progressive dyspnoea and an altered mental status. A high anion gap metabolic acidosis and acute lung injury was diagnosed. We hypothesise this was caused by GBL. In this case report we describe the diagnostic process and possible pathophysiological mechanisms that may have led to this life-threatening condition.
ISSN:	1872-9061