Fluorescent nuclear track detectors as a tool for ion-beam therapy research

Fluorescent nuclear track detectors based on Al2O3:C,Mg with their excellent efficiency for detection of heavy charged particles and full 3D information from laser scanning microscopy allow a multitude of issues related to ion-beam cancer therapy to be tackled. A recently established read out protoc...

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Veröffentlicht in:Radiation measurements 2013-09, Vol.56, p.267-272
Hauptverfasser: Greilich, S., Osinga, J.-M., Niklas, M., Lauer, F.M., Klimpki, G., Bestvater, F., Bartz, J.A., Akselrod, M.S., Jäkel, O.
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Sprache:eng
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Zusammenfassung:Fluorescent nuclear track detectors based on Al2O3:C,Mg with their excellent efficiency for detection of heavy charged particles and full 3D information from laser scanning microscopy allow a multitude of issues related to ion-beam cancer therapy to be tackled. A recently established read out protocol enables the utilization of a commercial microscope similar to those available in many life-science environments. This contribution illustrates the approach, its potential and limitations, as well as applications in clinical ion beams. ► Fluorescent nuclear track detectors (FNTDs) are based on alumina. ► They represent a unique research tool for ion beam cancer therapy. ► We present a protocol for FNTD read out using a commercial laser scanning microscope.
ISSN:1350-4487
1879-0925
DOI:10.1016/j.radmeas.2013.01.033