Core/shell nanoparticles in biomedical applications

Nanoparticles have several exciting applications in different areas and biomedial field is not an exception of that because of their exciting performance in bioimaging, targeted drug and gene delivery, sensors, and so on. It has been found that among several classes of nanoparticles core/shell is most promising for different biomedical applications because of several advantages over simple nanoparticles. This review highlights the development of core/shell nanoparticles-based biomedical research during approximately past two decades. Applications of different types of core/shell nanoparticles are classified in terms of five major aspects such as bioimaging, biosensor, targeted drug delivery, DNA/RNA interaction, and targeted gene delivery. [Display omitted] •Core/shell nanoparticles are extensively used for biomedical applications.•Shell is important for better dispersibility, bio-functionalization, and optical property.•Major applications are in bioimaging, drug delivery, gene delivery, and sensors.