Factorial design as tool in chitosan nanoparticles development by ionic gelation technique

Factorial design as tool in chitosan nanoparticles development by ionic gelation technique

•This work shows how to obtain chitosan nanoparticles with properties desired.•The formulation was optimized using a 23 factorial design.•Nanoparticles were obtained with size

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Veröffentlicht in:Colloids and surfaces. A, Physicochemical and engineering aspects Physicochemical and engineering aspects, 2014-03, Vol.445, p.34-39
Hauptverfasser: de Pinho Neves, Andréia Lange, Milioli, Camila Cardoso, Müller, Leidiani, Riella, Humberto Gracher, Kuhnen, Nivaldo Cabral, Stulzer, Hellen Karine
Format: Artikel
Sprache:eng
Schlagworte:
Charge
Chitosan
Experimental design
Factorial design
Formulations
Gelation
Ionic gelation
Nanoparticles
Nanostructure
Tripolyphosphate
Zeta potential
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Beschreibung
Zusammenfassung:•This work shows how to obtain chitosan nanoparticles with properties desired.•The formulation was optimized using a 23 factorial design.•Nanoparticles were obtained with size
ISSN:0927-7757
1873-4359
DOI:10.1016/j.colsurfa.2013.12.058