A Novel Red-Blood-Cell-Shaped Pectin-Oligochitosan Hydrogel System

A Novel Red-Blood-Cell-Shaped Pectin-Oligochitosan Hydrogel System

The biocompatible red‐blood‐cell‐shaped pectin–oligochitosan hydrogel capsule offers a large surface area to volume ratio, which improves transport capacity compared to the spherical one. This hydrogel capsule system can be used not merely for controlled delivery/release of bioactive agents, cell im...

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Veröffentlicht in:Particle & particle systems characterization 2014-09, Vol.31 (9), p.955-959
Hauptverfasser: Harvestine, Jenna Nicole, Mikulski, Brandon Anthony, Mahuta, Kirsten Mary, Crouse, James Zachary, Guo, Xiaoru, Lee, Jung Chull, Midelfort, Katarina Senn, Chen, Junhong, Zhang, Wujie
Format: Artikel
Sprache:eng
Schlagworte:
Biocompatibility
Blood
Capsule transport
capsules
chitosan
Encapsulation
Hydrogels
pectin
Red blood cells
Surface area
Tissue engineering
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Zusammenfassung:The biocompatible red‐blood‐cell‐shaped pectin–oligochitosan hydrogel capsule offers a large surface area to volume ratio, which improves transport capacity compared to the spherical one. This hydrogel capsule system can be used not merely for controlled delivery/release of bioactive agents, cell immobilization, or cell encapsulation towards regenerative medicine and tissue engineering, but also for creating artificial red blood cells/artificial blood.
ISSN:0934-0866
1521-4117
DOI:10.1002/ppsc.201400002