Polymorphism of 4-tert-butylcalix[4]arene upon formation of n-hexane and acetonitrile complexes and thermal desolvation

Simultaneous analysis of X-ray powder diffraction patterns and DSC traces for 4- tert -butylcalix[4]arene- n -hexane and 4- tert -butylcalix[4]arene-acetonitrile compounds as functions of thermal history allows us to reveal the complex relationship between guest-free polymorphic products and desolvation of 4- tert -butylcalix[4]arene inclusion compounds. Polymorphic transitions of t BC on uptake and thermal removal of n -hexane and acetonitrile were investigated using X-ray powder diffraction patterns and DSC traces to determine the relationship between guest-free polymorphic products and desolvation.