Neurophysiological features of motor cortex excitability and plasticity in Subcortical Ischemic Vascular Dementia: A TMS mapping study

Highlights • Motor cortex has enhanced excitability in AD and SIVD patients with respect to control subjects and it is plastically rearranged, without significant differences between the two demented groups. • In the whole sample of subjects examined a significant direct correlation between paramete...

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Veröffentlicht in:Clinical neurophysiology 2015-05, Vol.126 (5), p.906-913
Hauptverfasser: Guerra, Andrea, Petrichella, Sara, Vollero, Luca, Ponzo, David, Pasqualetti, Patrizio, Määttä, Sara, Mervaala, Esa, Könönen, Mervi, Bressi, Federica, Iannello, Giulio, Rossini, Paolo Maria, Ferreri, Florinda
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Sprache:eng
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Zusammenfassung:Highlights • Motor cortex has enhanced excitability in AD and SIVD patients with respect to control subjects and it is plastically rearranged, without significant differences between the two demented groups. • In the whole sample of subjects examined a significant direct correlation between parameters associated to cortical excitability and those associated to cortical plasticity is evident. • Common compensatory mechanisms may act in different kind of dementing diseases.
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2014.07.036