Structure-activity relationships of synthetic methyl oleanolate glycosides

Haemolytic activities of the five methyl oleanolate diglycosides were stronger than those of the nine monoglycosides. On the other hand, methyl oleanolate glucoside showed higher antibacterial activity against Staphylococcus aureus than the maltoside or the maltotrioside.

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Bibliographische Detailangaben
Veröffentlicht in:	Phytochemistry (Oxford) 1992, Vol.31 (11), p.3789-3791
Hauptverfasser:	Takechi, Masayuki, Tanaka, Yasuo
Format:	Artikel
Sprache:	eng
Schlagworte:	antibacterial activity antifungal activity antifungal agents antimicrobial agents Biological and medical sciences chemical reactions General pharmacology glycosides haemolysis hemolysis Medical sciences molecular conformation oleanolic acid Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments plant physiology saponin saponins Structure-activity relationships synthetic glycosides
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Beschreibung
Zusammenfassung:	Haemolytic activities of the five methyl oleanolate diglycosides were stronger than those of the nine monoglycosides. On the other hand, methyl oleanolate glucoside showed higher antibacterial activity against Staphylococcus aureus than the maltoside or the maltotrioside.
ISSN:	0031-9422 1873-3700
DOI:	10.1016/S0031-9422(00)97528-9