Single-Layer Transition Metal Dichalcogenide Nanosheet-Based Nanosensors for Rapid, Sensitive, and Multiplexed Detection of DNA

Single‐layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence‐quenching ability and different affinities toward single‐stranded DNA and double‐stranded DNA. I...

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Veröffentlicht in:Advanced materials (Weinheim) 2015-02, Vol.27 (5), p.935-939
Hauptverfasser: Zhang, Ying, Zheng, Bing, Zhu, Changfeng, Zhang, Xiao, Tan, Chaoliang, Li, Hai, Chen, Bo, Yang, Jian, Chen, Junze, Huang, Ying, Wang, Lianhui, Zhang, Hua
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container_issue 5
container_start_page 935
container_title Advanced materials (Weinheim)
container_volume 27
creator Zhang, Ying
Zheng, Bing
Zhu, Changfeng
Zhang, Xiao
Tan, Chaoliang
Li, Hai
Chen, Bo
Yang, Jian
Chen, Junze
Huang, Ying
Wang, Lianhui
Zhang, Hua
description Single‐layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence‐quenching ability and different affinities toward single‐stranded DNA and double‐stranded DNA. Importantly, for the first time, a single‐layer TaS2 nanosheet‐based multiplexed DNA sensor is also developed.
doi_str_mv 10.1002/adma.201404568
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subjects Affinity
Biosensing Techniques - methods
Chalcogens - chemistry
Deoxyribonucleic acid
DNA
DNA - analysis
DNA - chemistry
DNA Probes - chemistry
fluorescence
Limit of Detection
Models, Molecular
Molybdenum disulfide
multiplexed detection
Multiplexing
nanosheets
Nanostructure
Nanostructures - chemistry
Nanotechnology - methods
Nucleic Acid Conformation
Platforms
Sensors
Spectrometry, Fluorescence
Time Factors
Transition Elements - chemistry
transition metal dichalcogenides
Transition metals
title Single-Layer Transition Metal Dichalcogenide Nanosheet-Based Nanosensors for Rapid, Sensitive, and Multiplexed Detection of DNA
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