Single-Layer Transition Metal Dichalcogenide Nanosheet-Based Nanosensors for Rapid, Sensitive, and Multiplexed Detection of DNA
Single‐layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence‐quenching ability and different affinities toward single‐stranded DNA and double‐stranded DNA. I...
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Veröffentlicht in: | Advanced materials (Weinheim) 2015-02, Vol.27 (5), p.935-939 |
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container_title | Advanced materials (Weinheim) |
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creator | Zhang, Ying Zheng, Bing Zhu, Changfeng Zhang, Xiao Tan, Chaoliang Li, Hai Chen, Bo Yang, Jian Chen, Junze Huang, Ying Wang, Lianhui Zhang, Hua |
description | Single‐layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence‐quenching ability and different affinities toward single‐stranded DNA and double‐stranded DNA. Importantly, for the first time, a single‐layer TaS2 nanosheet‐based multiplexed DNA sensor is also developed. |
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Importantly, for the first time, a single‐layer TaS2 nanosheet‐based multiplexed DNA sensor is also developed.</description><identifier>ISSN: 0935-9648</identifier><identifier>EISSN: 1521-4095</identifier><identifier>DOI: 10.1002/adma.201404568</identifier><identifier>PMID: 25504749</identifier><language>eng</language><publisher>Germany: Blackwell Publishing Ltd</publisher><subject>Affinity ; Biosensing Techniques - methods ; Chalcogens - chemistry ; Deoxyribonucleic acid ; DNA ; DNA - analysis ; DNA - chemistry ; DNA Probes - chemistry ; fluorescence ; Limit of Detection ; Models, Molecular ; Molybdenum disulfide ; multiplexed detection ; Multiplexing ; nanosheets ; Nanostructure ; Nanostructures - chemistry ; Nanotechnology - methods ; Nucleic Acid Conformation ; Platforms ; Sensors ; Spectrometry, Fluorescence ; Time Factors ; Transition Elements - chemistry ; transition metal dichalcogenides ; Transition metals</subject><ispartof>Advanced materials (Weinheim), 2015-02, Vol.27 (5), p.935-939</ispartof><rights>2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><rights>2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5008-46fcf4b9073f2334f254c3bc75abe94c93e3ad342ad840f8ea9879dda8c8cb993</citedby><cites>FETCH-LOGICAL-c5008-46fcf4b9073f2334f254c3bc75abe94c93e3ad342ad840f8ea9879dda8c8cb993</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fadma.201404568$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fadma.201404568$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25504749$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Ying</creatorcontrib><creatorcontrib>Zheng, Bing</creatorcontrib><creatorcontrib>Zhu, Changfeng</creatorcontrib><creatorcontrib>Zhang, Xiao</creatorcontrib><creatorcontrib>Tan, Chaoliang</creatorcontrib><creatorcontrib>Li, Hai</creatorcontrib><creatorcontrib>Chen, Bo</creatorcontrib><creatorcontrib>Yang, Jian</creatorcontrib><creatorcontrib>Chen, Junze</creatorcontrib><creatorcontrib>Huang, Ying</creatorcontrib><creatorcontrib>Wang, Lianhui</creatorcontrib><creatorcontrib>Zhang, Hua</creatorcontrib><title>Single-Layer Transition Metal Dichalcogenide Nanosheet-Based Nanosensors for Rapid, Sensitive, and Multiplexed Detection of DNA</title><title>Advanced materials (Weinheim)</title><addtitle>Adv. Mater</addtitle><description>Single‐layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence‐quenching ability and different affinities toward single‐stranded DNA and double‐stranded DNA. Importantly, for the first time, a single‐layer TaS2 nanosheet‐based multiplexed DNA sensor is also developed.</description><subject>Affinity</subject><subject>Biosensing Techniques - methods</subject><subject>Chalcogens - chemistry</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA - analysis</subject><subject>DNA - chemistry</subject><subject>DNA Probes - chemistry</subject><subject>fluorescence</subject><subject>Limit of Detection</subject><subject>Models, Molecular</subject><subject>Molybdenum disulfide</subject><subject>multiplexed detection</subject><subject>Multiplexing</subject><subject>nanosheets</subject><subject>Nanostructure</subject><subject>Nanostructures - chemistry</subject><subject>Nanotechnology - methods</subject><subject>Nucleic Acid Conformation</subject><subject>Platforms</subject><subject>Sensors</subject><subject>Spectrometry, Fluorescence</subject><subject>Time Factors</subject><subject>Transition Elements - chemistry</subject><subject>transition metal dichalcogenides</subject><subject>Transition metals</subject><issn>0935-9648</issn><issn>1521-4095</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcFv0zAUhy0EYmVw5Yh85LCUl9hO7GNZWUG0RaxDHC3HftkMblLsFNYT_zrtMipu7GQ96fs-H36EvMxhnAMUb4xbm3EBOQcuSvmIjHJR5BkHJR6TESgmMlVyeUKepfQNAFQJ5VNyUggBvOJqRH6vfHsdMJubHUZ6FU2bfO-7li6wN4FOvb0xwXbX2HqHdGnaLt0g9tlbk9ANN7api4k2XaSXZuPdGV3hXeUnnlHTOrrYht5vAt7ujSn2aO8-6Bo6XU6ekyeNCQlf3L-n5MvFu6vz99n80-zD-WSeWQEgM142tuG1goo1BWO8KQS3rLaVMDUqbhVDZhzjhXGSQyPRKFkp54y00tZKsVPyeuhuYvdji6nXa58shmBa7LZJ52WppBQFg4egwJSSXDwAFQUXUMpDdTygNnYpRWz0Jvq1iTudgz5MqQ9T6uOUe-HVfXtbr9Ed8b_b7QE1AL98wN1_cnoyXUz-jWeD61OPt0fXxO-6rFgl9NflTK_4BZt9lJ_1JfsDQJS6Lg</recordid><startdate>20150201</startdate><enddate>20150201</enddate><creator>Zhang, Ying</creator><creator>Zheng, Bing</creator><creator>Zhu, Changfeng</creator><creator>Zhang, Xiao</creator><creator>Tan, Chaoliang</creator><creator>Li, Hai</creator><creator>Chen, Bo</creator><creator>Yang, Jian</creator><creator>Chen, Junze</creator><creator>Huang, Ying</creator><creator>Wang, Lianhui</creator><creator>Zhang, Hua</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TM</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope></search><sort><creationdate>20150201</creationdate><title>Single-Layer Transition Metal Dichalcogenide Nanosheet-Based Nanosensors for Rapid, Sensitive, and Multiplexed Detection of DNA</title><author>Zhang, Ying ; Zheng, Bing ; Zhu, Changfeng ; Zhang, Xiao ; Tan, Chaoliang ; Li, Hai ; Chen, Bo ; Yang, Jian ; Chen, Junze ; Huang, Ying ; Wang, Lianhui ; Zhang, Hua</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5008-46fcf4b9073f2334f254c3bc75abe94c93e3ad342ad840f8ea9879dda8c8cb993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Affinity</topic><topic>Biosensing Techniques - methods</topic><topic>Chalcogens - chemistry</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA - analysis</topic><topic>DNA - chemistry</topic><topic>DNA Probes - chemistry</topic><topic>fluorescence</topic><topic>Limit of Detection</topic><topic>Models, Molecular</topic><topic>Molybdenum disulfide</topic><topic>multiplexed detection</topic><topic>Multiplexing</topic><topic>nanosheets</topic><topic>Nanostructure</topic><topic>Nanostructures - chemistry</topic><topic>Nanotechnology - methods</topic><topic>Nucleic Acid Conformation</topic><topic>Platforms</topic><topic>Sensors</topic><topic>Spectrometry, Fluorescence</topic><topic>Time Factors</topic><topic>Transition Elements - chemistry</topic><topic>transition metal dichalcogenides</topic><topic>Transition metals</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Ying</creatorcontrib><creatorcontrib>Zheng, Bing</creatorcontrib><creatorcontrib>Zhu, Changfeng</creatorcontrib><creatorcontrib>Zhang, Xiao</creatorcontrib><creatorcontrib>Tan, Chaoliang</creatorcontrib><creatorcontrib>Li, Hai</creatorcontrib><creatorcontrib>Chen, Bo</creatorcontrib><creatorcontrib>Yang, Jian</creatorcontrib><creatorcontrib>Chen, Junze</creatorcontrib><creatorcontrib>Huang, Ying</creatorcontrib><creatorcontrib>Wang, Lianhui</creatorcontrib><creatorcontrib>Zhang, Hua</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Nucleic Acids Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>Advanced materials (Weinheim)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Ying</au><au>Zheng, Bing</au><au>Zhu, Changfeng</au><au>Zhang, Xiao</au><au>Tan, Chaoliang</au><au>Li, Hai</au><au>Chen, Bo</au><au>Yang, Jian</au><au>Chen, Junze</au><au>Huang, Ying</au><au>Wang, Lianhui</au><au>Zhang, Hua</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Single-Layer Transition Metal Dichalcogenide Nanosheet-Based Nanosensors for Rapid, Sensitive, and Multiplexed Detection of DNA</atitle><jtitle>Advanced materials (Weinheim)</jtitle><addtitle>Adv. Mater</addtitle><date>2015-02-01</date><risdate>2015</risdate><volume>27</volume><issue>5</issue><spage>935</spage><epage>939</epage><pages>935-939</pages><issn>0935-9648</issn><eissn>1521-4095</eissn><abstract>Single‐layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence‐quenching ability and different affinities toward single‐stranded DNA and double‐stranded DNA. Importantly, for the first time, a single‐layer TaS2 nanosheet‐based multiplexed DNA sensor is also developed.</abstract><cop>Germany</cop><pub>Blackwell Publishing Ltd</pub><pmid>25504749</pmid><doi>10.1002/adma.201404568</doi><tpages>5</tpages></addata></record> |
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subjects | Affinity Biosensing Techniques - methods Chalcogens - chemistry Deoxyribonucleic acid DNA DNA - analysis DNA - chemistry DNA Probes - chemistry fluorescence Limit of Detection Models, Molecular Molybdenum disulfide multiplexed detection Multiplexing nanosheets Nanostructure Nanostructures - chemistry Nanotechnology - methods Nucleic Acid Conformation Platforms Sensors Spectrometry, Fluorescence Time Factors Transition Elements - chemistry transition metal dichalcogenides Transition metals |
title | Single-Layer Transition Metal Dichalcogenide Nanosheet-Based Nanosensors for Rapid, Sensitive, and Multiplexed Detection of DNA |
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