Single-Layer Transition Metal Dichalcogenide Nanosheet-Based Nanosensors for Rapid, Sensitive, and Multiplexed Detection of DNA

Single-Layer Transition Metal Dichalcogenide Nanosheet-Based Nanosensors for Rapid, Sensitive, and Multiplexed Detection of DNA

Single‐layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence‐quenching ability and different affinities toward single‐stranded DNA and double‐stranded DNA. I...

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Veröffentlicht in:Advanced materials (Weinheim) 2015-02, Vol.27 (5), p.935-939
Hauptverfasser: Zhang, Ying, Zheng, Bing, Zhu, Changfeng, Zhang, Xiao, Tan, Chaoliang, Li, Hai, Chen, Bo, Yang, Jian, Chen, Junze, Huang, Ying, Wang, Lianhui, Zhang, Hua
Format: Artikel
Sprache:eng
Schlagworte:
Affinity
Biosensing Techniques - methods
Chalcogens - chemistry
Deoxyribonucleic acid
DNA
DNA - analysis
DNA - chemistry
DNA Probes - chemistry
fluorescence
Limit of Detection
Models, Molecular
Molybdenum disulfide
multiplexed detection
Multiplexing
nanosheets
Nanostructure
Nanostructures - chemistry
Nanotechnology - methods
Nucleic Acid Conformation
Platforms
Sensors
Spectrometry, Fluorescence
Time Factors
Transition Elements - chemistry
transition metal dichalcogenides
Transition metals
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Zusammenfassung:Single‐layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence‐quenching ability and different affinities toward single‐stranded DNA and double‐stranded DNA. Importantly, for the first time, a single‐layer TaS2 nanosheet‐based multiplexed DNA sensor is also developed.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201404568