A magnetic polyaniline nanohybrid for MR imaging and redox sensing of cancer cells

A synthetic process for constructing an organo-metal nanohybrid is described. This process uses polyaniline as a ligand in order to fabricate magnetic nanoparticles. This nanohybrid shows imaging potential uses as a magnetic resonance imaging contrast agent and a redox-sensing probe simultaneously b...

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Veröffentlicht in:Nanoscale 2015-02, Vol.7 (5), p.1661-1666
Hauptverfasser: Hong, Yoochan, Hwang, Seungyeon, Heo, Dan, Kim, Bongjune, Ku, Minhee, Lee, Eugene, Haam, Seungjoo, Yoon, Dae Sung, Yang, Jaemoon, Suh, Jin-Suck
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container_end_page 1666
container_issue 5
container_start_page 1661
container_title Nanoscale
container_volume 7
creator Hong, Yoochan
Hwang, Seungyeon
Heo, Dan
Kim, Bongjune
Ku, Minhee
Lee, Eugene
Haam, Seungjoo
Yoon, Dae Sung
Yang, Jaemoon
Suh, Jin-Suck
description A synthetic process for constructing an organo-metal nanohybrid is described. This process uses polyaniline as a ligand in order to fabricate magnetic nanoparticles. This nanohybrid shows imaging potential uses as a magnetic resonance imaging contrast agent and a redox-sensing probe simultaneously both in vitro and in vivo.
doi_str_mv 10.1039/c4nr06340f
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source MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection
subjects Aniline Compounds - chemistry
Animals
Biomedical materials
Cell Line, Tumor
Cell Survival - drug effects
Contrast Media - chemistry
Contrast Media - pharmacology
Contrast Media - toxicity
Humans
Imaging
In vivo testing
In vivo tests
Ligands
Magnetic Resonance Imaging
Magnetics
Matrix Metalloproteinase 1 - metabolism
MCF-7 Cells
Mice
Nanoparticles
Nanoparticles - chemistry
Nanostructure
Neoplasms - diagnostic imaging
Neoplasms - pathology
Oxidation-Reduction
Polyanilines
Radiography
Transplantation, Heterologous
title A magnetic polyaniline nanohybrid for MR imaging and redox sensing of cancer cells
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