A magnetic polyaniline nanohybrid for MR imaging and redox sensing of cancer cells

A synthetic process for constructing an organo-metal nanohybrid is described. This process uses polyaniline as a ligand in order to fabricate magnetic nanoparticles. This nanohybrid shows imaging potential uses as a magnetic resonance imaging contrast agent and a redox-sensing probe simultaneously b...

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Veröffentlicht in:	Nanoscale 2015-02, Vol.7 (5), p.1661-1666
Hauptverfasser:	Hong, Yoochan, Hwang, Seungyeon, Heo, Dan, Kim, Bongjune, Ku, Minhee, Lee, Eugene, Haam, Seungjoo, Yoon, Dae Sung, Yang, Jaemoon, Suh, Jin-Suck
Format:	Artikel
Sprache:	eng
Schlagworte:	Aniline Compounds - chemistry Animals Biomedical materials Cell Line, Tumor Cell Survival - drug effects Contrast Media - chemistry Contrast Media - pharmacology Contrast Media - toxicity Humans Imaging In vivo testing In vivo tests Ligands Magnetic Resonance Imaging Magnetics Matrix Metalloproteinase 1 - metabolism MCF-7 Cells Mice Nanoparticles Nanoparticles - chemistry Nanostructure Neoplasms - diagnostic imaging Neoplasms - pathology Oxidation-Reduction Polyanilines Radiography Transplantation, Heterologous
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Beschreibung
Zusammenfassung:	A synthetic process for constructing an organo-metal nanohybrid is described. This process uses polyaniline as a ligand in order to fabricate magnetic nanoparticles. This nanohybrid shows imaging potential uses as a magnetic resonance imaging contrast agent and a redox-sensing probe simultaneously both in vitro and in vivo.
ISSN:	2040-3364 2040-3372
DOI:	10.1039/c4nr06340f