A near-infrared light-controlled system for reversible presentation of bioactive ligands using polypeptide-engineered functionalized gold nanorods

A near-infrared light-controlled system for reversible presentation of bioactive ligands using polypeptide-engineered functionalized gold nanorods

A near-infrared light-controlled hybrid platform with polypeptide-engineered functionalized gold nanorods has been designed for reversible presentation of the immobilized ligands to cell surface receptors on the engineered materials.

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Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2015-02, Vol.51 (13), p.2569-2572
Hauptverfasser: Yang, Jie, Yao, Ming-Hao, Du, Ming-Shuo, Jin, Rui-Mei, Zhao, Dong-Hui, Ma, Jun, Ma, Zhi-Ya, Zhao, Yuan-Di, Liu, Bo
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biocompatibility
Cell Survival - drug effects
Dose-Response Relationship, Drug
Gold
Gold - chemistry
Gold - pharmacology
Infrared Rays
Ligands
Mice
Nanorods
Nanotubes - chemistry
NIH 3T3 Cells
Peptides - chemistry
Peptides - pharmacology
Platforms
Protein Engineering
Receptors
Structure-Activity Relationship
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Beschreibung
Zusammenfassung:A near-infrared light-controlled hybrid platform with polypeptide-engineered functionalized gold nanorods has been designed for reversible presentation of the immobilized ligands to cell surface receptors on the engineered materials.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc09516b