A Fast and Activatable Cross-Linking Strategy for Hydrogel Formation
Strain‐promoted oxidation‐controlled cyclooctyne‐1,2‐quinone cycloaddition (SPOCQ) is a fast and activatable cross‐linking strategy for hydrogel formation. Gelation is induced by oxidation, which is performed both chemically using sodium periodate and enzymatically using mushroom tyrosinase. Due to...
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| Veröffentlicht in: | Advanced materials (Weinheim) 2015-02, Vol.27 (7), p.1235-1240 |
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| container_title | Advanced materials (Weinheim) |
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| creator | Jonker, Anika M. Borrmann, Annika van Eck, Ernst R. H. van Delft, Floris L. Löwik, Dennis W. P. M. van Hest, Jan C. M. |
| description | Strain‐promoted oxidation‐controlled cyclooctyne‐1,2‐quinone cycloaddition (SPOCQ) is a fast and activatable cross‐linking strategy for hydrogel formation. Gelation is induced by oxidation, which is performed both chemically using sodium periodate and enzymatically using mushroom tyrosinase. Due to the fast reaction kinetics, SPOCQ‐formed hydrogels can be functionalized in one‐pot with an azido‐containing moiety using SPAAC cross‐linking. |
| doi_str_mv | 10.1002/adma.201404448 |
| format | Article |
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Due to the fast reaction kinetics, SPOCQ‐formed hydrogels can be functionalized in one‐pot with an azido‐containing moiety using SPAAC cross‐linking.</description><subject>activatable</subject><subject>cross-linking</subject><subject>Crosslinking</subject><subject>Cycloaddition</subject><subject>Formations</subject><subject>hydrogel</subject><subject>Hydrogels</subject><subject>Mushrooms</subject><subject>oxidation</subject><subject>Sodium</subject><subject>Strategy</subject><subject>Tyrosinase</subject><issn>0935-9648</issn><issn>1521-4095</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqNkDtPwzAURi0EglJYGVFGlhS_Y4-hpS1SgQEQo-U4N1UgD7BToP-eVi0VG0x3Od-R7kHojOABwZhe2ry2A4oJx5xztYd6RFASc6zFPuphzUSsJVdH6DiEF4yxllgeoiMqBBOY0R4apdHYhi6yTR6lris_bGezCqKhb0OIZ2XzWjbz6KHztoP5MipaH02XuW_nUEXj1te2K9vmBB0Utgpwur199DS-fhxO49n95GaYzmIntVaxhSIjnDhKScYoUKKISkBqmgihcue0Ap7lmaNOWnDEWZZwncncFkphEIT10cXG--bb9wWEztRlcFBVtoF2EQyRUitBEqr-gQqRUMlIskIHG9Stf_ZQmDdf1tYvDcFmHdmsI5td5NXgfOteZDXkO_yn6grQG-CzrGD5h86ko9v0tzzebMvQwddua_2rkQlLhHm-mxihxtMZv1JmxL4BO3iWWw</recordid><startdate>20150218</startdate><enddate>20150218</enddate><creator>Jonker, Anika M.</creator><creator>Borrmann, Annika</creator><creator>van Eck, Ernst R. 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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | activatable cross-linking Crosslinking Cycloaddition Formations hydrogel Hydrogels Mushrooms oxidation Sodium Strategy Tyrosinase |
| title | A Fast and Activatable Cross-Linking Strategy for Hydrogel Formation |
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