Safety of vaccine adjuvants: Focus on autoimmunity

Highlights • Industrial, academic, and governmental experts studied vaccine adjuvants safety. • Evidence of signals for autoimmune disorders associated with adjuvants was reviewed. • Existing adjuvants (used in marketed vaccines) and novel adjuvants were included. • The focus was on oil-in-water emu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2015-03, Vol.33 (13), p.1507-1514
Hauptverfasser:	van der Laan, Jan Willem, Gould, Sarah, Tanir, Jennifer Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Academies and Institutes Adjuvants, Immunologic - adverse effects Allergy and Immunology Animal models Animals Autoimmune Diseases - immunology Autoimmunity Biomarkers Humans Models, Animal Risk Assessment Safety Vaccine adjuvants Vaccines Vaccines - adverse effects Vaccines - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Industrial, academic, and governmental experts studied vaccine adjuvants safety. • Evidence of signals for autoimmune disorders associated with adjuvants was reviewed. • Existing adjuvants (used in marketed vaccines) and novel adjuvants were included. • The focus was on oil-in-water emulsion and toll-like receptor agonist adjuvants. • No compelling evidence was found associating adjuvants and autoimmunity in humans.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2015.01.073