Vitamin D Levels and Cognition in Elderly Adults in China

Objectives To evaluate the association between vitamin D level and cognitive impairment in individuals aged 60 and older. Design Cross‐sectional cohort study. Setting Chinese Longitudinal Healthy Longevity Survey, a community‐based cohort study in areas in China where the density of centenarians is...

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Veröffentlicht in:	Journal of the American Geriatrics Society (JAGS) 2014-11, Vol.62 (11), p.2125-2129
Hauptverfasser:	Chei, Choy-Lye, Raman, Prassanna, Yin, Zhao-Xue, Shi, Xiao-Ming, Zeng, Yi, Matchar, David B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - blood Alzheimer Disease - ethnology Biological and medical sciences Calcifediol - blood China cognition Cognition & reasoning Cross-Cultural Comparison Cross-Sectional Studies elderly Female General aspects Geriatrics Humans Longevity Male Medical sciences Mental Status Schedule Middle Aged Miscellaneous Multivariate Analysis Odds Ratio oldest old Public health. Hygiene Public health. Hygiene-occupational medicine Statistics as Topic Vitamin D Vitamin D Deficiency - blood Vitamin D Deficiency - ethnology
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Zusammenfassung:	Objectives To evaluate the association between vitamin D level and cognitive impairment in individuals aged 60 and older. Design Cross‐sectional cohort study. Setting Chinese Longitudinal Healthy Longevity Survey, a community‐based cohort study in areas in China where the density of centenarians is exceptionally high. Participants Individuals with mean age of 84.9 ± 12.7 (N = 2,004). Measurements Participants’ cognitive state was evaluated using the Mini‐Mental State Examination (MMSE). Vitamin D was measured in plasma using an enzyme‐linked immunoassay. Results The cross‐sectional association between quartiles of plasma vitamin D level and cognitive impairment (MMSE score
ISSN:	0002-8614 1532-5415
DOI:	10.1111/jgs.13082