Effects of lindane exposure on rainbow trout (Oncorhynchus mykiss) immunity: 2. In vitro restoration of antibody-secreting cells and lymphocyte proliferation activity by nitrogranulogen after in vivo immunosuppression due to lindane

Effects of lindane exposure on rainbow trout (Oncorhynchus mykiss) immunity: 2. In vitro restoration of antibody-secreting cells and lymphocyte proliferation activity by nitrogranulogen after in vivo immunosuppression due to lindane

A dose-dependent immunomodulatory effect of Nitrogranulogen (NGG) was observed in vitro on antibody-secreting cells and lymphocyte proliferation in rainbow trout. Because different doses of lindane (10, 50 and 100 mg/kg, injected intraperitoneally) had a depressing effect on the same immune function...

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Veröffentlicht in:Ecotoxicology and environmental safety 1994-04, Vol.27 (3), p.316-323
Hauptverfasser: Siwicki, A K, Dunier, M
Format: Artikel
Sprache:eng
Schlagworte:
Freshwater
Oncorhynchus mykiss
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Zusammenfassung:A dose-dependent immunomodulatory effect of Nitrogranulogen (NGG) was observed in vitro on antibody-secreting cells and lymphocyte proliferation in rainbow trout. Because different doses of lindane (10, 50 and 100 mg/kg, injected intraperitoneally) had a depressing effect on the same immune functions, the authors restored them using NGG in vitro.
ISSN:0147-6513
DOI:10.1006/eesa.1994.1025