Don’t edit the human germ line

Heritable human genetic modifications pose serious risks, and the therapeutic benefits are tenuous, warn Edward Lanphier, Fyodor Urnov and colleagues.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2015-03, Vol.519 (7544), p.410-411
Hauptverfasser:	Lanphier, Edward, Urnov, Fyodor, Haecker, Sarah Ehlen, Werner, Michael, Smolenski, Joanna
Format:	Artikel
Sprache:	eng
Schlagworte:	631/61 692/700/565 706/648/453 706/689/179 Bioethics comment Communication CRISPR-Cas Systems Deoxyribonucleic acid DNA Embryo Research - ethics Embryos Endonucleases - metabolism Genes Genetic engineering Genetic Engineering - ethics Genome, Human - genetics Genomes Germ Cells - metabolism Germ-Line Mutation - genetics Humanities and Social Sciences Humans Mitochondrial DNA multidisciplinary Mutation Nonprofit organizations Patient safety Patient Safety - standards Patients Practice Guidelines as Topic Research institutions Research Personnel - ethics Risk Assessment - ethics Risk Assessment - standards Science Science (multidisciplinary) Studies Zinc Fingers
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Beschreibung
Zusammenfassung:	Heritable human genetic modifications pose serious risks, and the therapeutic benefits are tenuous, warn Edward Lanphier, Fyodor Urnov and colleagues.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/519410a