Outcomes of minimally invasive simple prostatectomy for benign prostatic hyperplasia: a systematic review and meta-analysis

Purpose (1) To assess the outcomes of minimally invasive simple prostatectomy (MISP) for the treatment of symptomatic benign prostatic hyperplasia in men with large prostates and (2) to compare them with open simple prostatectomy (OSP). Methods A systematic review of outcomes of MISP for benign prostatic hyperplasia with meta-analysis was conducted. The article selection process was conducted according to the PRISMA guidelines. Results Twenty-seven observational studies with 764 patients were analyzed. The mean prostate volume was 113.5 ml (95 % CI 106–121). The mean increase in Qmax was 14.3 ml/s (95 % CI 13.1–15.6), and the mean improvement in IPSS was 17.2 (95 % CI 15.2–19.2). Mean duration of operation was 141 min (95 % CI 124–159), and the mean intraoperative blood loss was 284 ml (95 % CI 243–325). One hundred and four patients (13.6 %) developed a surgical complication. In comparative studies, length of hospital stay (WMD −1.6 days, p = 0.02), length of catheter use (WMD −1.3 days, p = 0.04) and estimated blood loss (WMD −187 ml, p = 0.015) were significantly lower in the MISP group, while the duration of operation was longer than in OSP (WMD 37.8 min, p