A Comprehensive Metabolic Model for Uranium Metabolism and Dosimetry Based on Human and Animal Data

A pharmacokinetic model of uranium metabolism suitable both for bioassay and dosimetric purposes has been developed incorporating recycling between organs and plasma. This model is consistent with the information on uranium metabolism in both animals and man, and applicable to man. Excretion of U is...

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Veröffentlicht in:	Radiation protection dosimetry 1994-01, Vol.53 (1-4), p.255-258
Hauptverfasser:	Wrenn, M.E., Bertelli, L., Durbin, P.W., Singh, N.P., Lipsztein, J.L., Eckerman, K.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied radiobiology (equipment, dosimetry...) Biological and medical sciences Biological effects of radiation Fundamental and applied biological sciences. Psychology Tissues, organs and organisms biophysics
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Beschreibung
Zusammenfassung:	A pharmacokinetic model of uranium metabolism suitable both for bioassay and dosimetric purposes has been developed incorporating recycling between organs and plasma. This model is consistent with the information on uranium metabolism in both animals and man, and applicable to man. Excretion of U is almost 100% urinary. The model consists of a systematic part integrated with respiratory and gastrointestinal tracts.
ISSN:	0144-8420 1742-3406
DOI:	10.1093/oxfordjournals.rpd.a082287