Pulmonary surfactant in the airway physiology: A direct relaxing effect on the smooth muscle

Highlights • Airway surfactant has an important role in the respiratory physiology. • Surfactant directly relaxes airway smooth muscle. • Surfactant dysfunction may be included in the pathophysiology of asthma, COPD or other diseases with bronchial obstruction.

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Veröffentlicht in:Respiratory physiology & neurobiology 2015-04, Vol.209, p.95-105
Hauptverfasser: Calkovska, A, Uhliarova, B, Joskova, M, Franova, S, Kolomaznik, M, Calkovsky, V, Smolarova, S
Format: Artikel
Sprache:eng
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Zusammenfassung:Highlights • Airway surfactant has an important role in the respiratory physiology. • Surfactant directly relaxes airway smooth muscle. • Surfactant dysfunction may be included in the pathophysiology of asthma, COPD or other diseases with bronchial obstruction.
ISSN:1569-9048
1878-1519
DOI:10.1016/j.resp.2015.01.004