Cortico-muscular coherence in advanced Parkinson’s disease with deep brain stimulation

Highlights • Deep brain stimulation (DBS) modifies the cortico-muscular coherence (CMC) in advanced Parkinson’s disease with high individual variability. • No clear correlation between CMC and total motor performance was detected. • CMC between 13 and 25 Hz was associated with better UPDRS (Unified...

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Veröffentlicht in:	Clinical neurophysiology 2015-04, Vol.126 (4), p.748-755
Hauptverfasser:	Airaksinen, Katja, Mäkelä, Jyrki P, Nurminen, Jussi, Luoma, Jarkko, Taulu, Samu, Ahonen, Antti, Pekkonen, Eero
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cerebral Cortex - physiopathology Cortico-muscular coherence Deep brain stimulation Deep Brain Stimulation - methods Electromyography - methods Female Humans Levodopa - therapeutic use Magnetoencephalography Magnetoencephalography - methods Male Middle Aged Muscle Rigidity - diagnosis Muscle Rigidity - physiopathology Muscle Rigidity - therapy Muscle, Skeletal - physiopathology Neurology Parkinson disease Parkinson Disease - diagnosis Parkinson Disease - physiopathology Parkinson Disease - therapy Rigidity Subthalamic nucleus Subthalamic Nucleus - physiopathology Tremor - diagnosis Tremor - physiopathology Tremor - therapy
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Zusammenfassung:	Highlights • Deep brain stimulation (DBS) modifies the cortico-muscular coherence (CMC) in advanced Parkinson’s disease with high individual variability. • No clear correlation between CMC and total motor performance was detected. • CMC between 13 and 25 Hz was associated with better UPDRS (Unified Parkinson disease scores) results at the group level in both DBS on and off conditions.
ISSN:	1388-2457 1872-8952
DOI:	10.1016/j.clinph.2014.07.025