Spinal nerve involvement in early Guillain–Barré syndrome: A clinico-electrophysiological, ultrasonographic and pathological study

Highlights • We carried out clinical-electrophysiological evaluation, and ultrasonography of peripheral nerves and cervical nerves in 6 early Guillain–Barré patients, with detailed autopsy study in one of them. • Involvement of spinal nerves was an outstanding finding. • Inflammatory oedema of spina...

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Veröffentlicht in:	Clinical neurophysiology 2015-04, Vol.126 (4), p.810-819
Hauptverfasser:	Gallardo, Elena, Sedano, María J, Orizaola, Pedro, Sánchez-Juan, Pascual, González-Suárez, Andrea, García, Antonio, Terán-Villagrá, Nuria, Ruiz-Soto, María, Álvaro, Rosa Landeras, Berciano, María T, Lafarga, Miguel, Berciano, José
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over AIDP AMAN AMSAN Antiganglioside antibody Axonal degeneration Demyelination Early Diagnosis Electrophysiological Phenomena - physiology Electrophysiology Endoneurial oedema Experimental allergic neuritis Female Guillain-Barre Syndrome - diagnostic imaging Guillain-Barre Syndrome - physiopathology Guillain–Barré syndrome Humans Male Methylprednisolone Middle Aged Neurology Spinal Nerves - diagnostic imaging Spinal Nerves - physiopathology Ultrasonography
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Zusammenfassung:	Highlights • We carried out clinical-electrophysiological evaluation, and ultrasonography of peripheral nerves and cervical nerves in 6 early Guillain–Barré patients, with detailed autopsy study in one of them. • Involvement of spinal nerves was an outstanding finding. • Inflammatory oedema of spinal nerves is a pathogenically relevant feature to understanding the mechanism of ascending paralysis.
ISSN:	1388-2457 1872-8952
DOI:	10.1016/j.clinph.2014.06.051