Enabling plant synthetic biology through genome engineering

Highlights • Rewriting genomes will play an important role in plant synthetic biology. • Sequence-specific nucleases enable almost any DNA sequence change in plant cells. • The advantages and limitations of current sequence-specific nucleases are discussed. • A comprehensive list of recent plant gen...

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Veröffentlicht in:	Trends in biotechnology (Regular ed.) 2015-02, Vol.33 (2), p.120-131
Hauptverfasser:	Baltes, Nicholas J, Voytas, Daniel F
Format:	Artikel
Sprache:	eng
Schlagworte:	Agrobacterium - genetics Climate change CRISPR/Cas Deoxyribonucleic acid Design DNA DNA End-Joining Repair Endonucleases - genetics Gene expression Gene Expression Regulation, Plant Gene Targeting - methods Genetic engineering Genetic Engineering - methods genome engineering Genome, Plant Genomes Genomics Homologous Recombination Internal Medicine Metabolites Methods Mutagenesis, Site-Directed - methods Nitrogen Fixation - genetics Organisms Plants - genetics sequence-specific nuclease Signal transduction Synthetic biology Synthetic Biology - methods TALEN Tobacco Zinc Fingers - genetics zinc-finger nuclease
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Beschreibung
Zusammenfassung:	Highlights • Rewriting genomes will play an important role in plant synthetic biology. • Sequence-specific nucleases enable almost any DNA sequence change in plant cells. • The advantages and limitations of current sequence-specific nucleases are discussed. • A comprehensive list of recent plant genome engineering achievements is provided. • Achievements in genome engineering are related to plant synthetic biology projects.
ISSN:	0167-7799 1879-3096
DOI:	10.1016/j.tibtech.2014.11.008