Why worms watch their hemidesmosomes and why you should, too

Hemidesmosomes are cellular attachment structures of great importance to the epidermis. In this issue of Immunity, Zhang et al. (2015) have discovered that in addition to having structural functions, invertebrate and human hemidesmosomes are actively monitored by the cell as a novel mechanism for de...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2015-02, Vol.42 (2), p.206-208
1. Verfasser:	Irazoqui, Javier E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimicrobial Cationic Peptides - biosynthesis Caenorhabditis elegans - immunology Caenorhabditis elegans Proteins - metabolism Defense Epidermis - immunology Epidermis - injuries Experiments Gene expression Genetic engineering Humans Hypotheses Infections Kinases Laboratories Nematodes Skin STAT Transcription Factors - metabolism Surveillance Transcription factors Worms
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Beschreibung
Zusammenfassung:	Hemidesmosomes are cellular attachment structures of great importance to the epidermis. In this issue of Immunity, Zhang et al. (2015) have discovered that in addition to having structural functions, invertebrate and human hemidesmosomes are actively monitored by the cell as a novel mechanism for detecting pathogenic infection.
ISSN:	1074-7613 1097-4180
DOI:	10.1016/j.immuni.2015.01.021