Synthesis and antifungal activity of analogues of naturally occurring botrydial precursors
Analog compounds of the proposed intermediates of the biogenetic pathway to botrydial have been synthesized. These compounds were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea. Our results showed a fungistatic effect of some compounds on mycelium growth. T...
Gespeichert in:
| Veröffentlicht in: | Journal of chemical ecology 1994-10, Vol.20 (10), p.2631-2644 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2644 |
|---|---|
| container_issue | 10 |
| container_start_page | 2631 |
| container_title | Journal of chemical ecology |
| container_volume | 20 |
| creator | COLLADO, I. G ALEU, J MACIAS-SANCHEZ, A. J HERNANDEZ-GALAN, R |
| description | Analog compounds of the proposed intermediates of the biogenetic pathway to botrydial have been synthesized. These compounds were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea. Our results showed a fungistatic effect of some compounds on mycelium growth. The most significant effect was exerted by 2-alpha-hydroxy-2,3-dihydro-1-epiprobotrydial, which inhibited growth of B. cinerea. Some aspects of structure-activity relationships are discussed. |
| doi_str_mv | 10.1007/BF02036197 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_16632800</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1459565492</sourcerecordid><originalsourceid>FETCH-LOGICAL-c368t-61983651244a694ea0bd4245511f5f979d14277372511db34b0944541b07344b3</originalsourceid><addsrcrecordid>eNp9kUtLxDAUhYMoOj42_gCZhYgI1Zt3s9TBUWHAxejGTUnbdIx02jFphf577-A47lyEkJMvh3NPCDmlcE0B9M3dFBhwRY3eISMqNU-oVHSXjABMmgDn9IAcxvgBAEylcp8cMMEETbkekbf50HTvLvo4tk2Jq_NV3yxsPbZF5798N4zbCmVbt4vexfWhsV0fbF3jTVH0IfhmMc7bLgylx2er4FCMbYjHZK-ydXQnm_2IvE7vXyaPyez54WlyO0sKrtIuwdwpV5IyIawywlnIS4wnJaWVrIw2JRVMa64ZKmXORQ5GCCloDpoLkfMjcvHjuwrtJ2bssqWPhatr27i2jxlVirMUAMHL_0EhjVRSGIbo1Q9ahDbG4KpsFfzShiGjkK1Lz_5KR_hs49vnS1du0d-WETjfADYWtq6CbQoftxzH2QSWsPWpbJvZRUDkdU6NUfiP2Azn3-HukGc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1459565492</pqid></control><display><type>article</type><title>Synthesis and antifungal activity of analogues of naturally occurring botrydial precursors</title><source>SpringerLink Journals - AutoHoldings</source><creator>COLLADO, I. G ; ALEU, J ; MACIAS-SANCHEZ, A. J ; HERNANDEZ-GALAN, R</creator><creatorcontrib>COLLADO, I. G ; ALEU, J ; MACIAS-SANCHEZ, A. J ; HERNANDEZ-GALAN, R ; Universidad de Cadiz, Cadiz, Spain</creatorcontrib><description>Analog compounds of the proposed intermediates of the biogenetic pathway to botrydial have been synthesized. These compounds were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea. Our results showed a fungistatic effect of some compounds on mycelium growth. The most significant effect was exerted by 2-alpha-hydroxy-2,3-dihydro-1-epiprobotrydial, which inhibited growth of B. cinerea. Some aspects of structure-activity relationships are discussed.</description><identifier>ISSN: 0098-0331</identifier><identifier>EISSN: 1573-1561</identifier><identifier>DOI: 10.1007/BF02036197</identifier><identifier>PMID: 24241837</identifier><identifier>CODEN: JCECD8</identifier><language>eng</language><publisher>New York, NY: Springer</publisher><subject>Biological and medical sciences ; Botrytis cinerea ; Chemical control ; Control ; fongicide ; Fundamental and applied biological sciences. Psychology ; Fungal plant pathogens ; fungicidas ; fungicides ; metabolite ; metabolites ; metabolitos ; Phytopathology. Animal pests. Plant and forest protection ; sesquiterpenoide ; sesquiterpenoids ; sesquiterpenos</subject><ispartof>Journal of chemical ecology, 1994-10, Vol.20 (10), p.2631-2644</ispartof><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c368t-61983651244a694ea0bd4245511f5f979d14277372511db34b0944541b07344b3</citedby><cites>FETCH-LOGICAL-c368t-61983651244a694ea0bd4245511f5f979d14277372511db34b0944541b07344b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3372498$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24241837$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>COLLADO, I. G</creatorcontrib><creatorcontrib>ALEU, J</creatorcontrib><creatorcontrib>MACIAS-SANCHEZ, A. J</creatorcontrib><creatorcontrib>HERNANDEZ-GALAN, R</creatorcontrib><creatorcontrib>Universidad de Cadiz, Cadiz, Spain</creatorcontrib><title>Synthesis and antifungal activity of analogues of naturally occurring botrydial precursors</title><title>Journal of chemical ecology</title><addtitle>J Chem Ecol</addtitle><description>Analog compounds of the proposed intermediates of the biogenetic pathway to botrydial have been synthesized. These compounds were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea. Our results showed a fungistatic effect of some compounds on mycelium growth. The most significant effect was exerted by 2-alpha-hydroxy-2,3-dihydro-1-epiprobotrydial, which inhibited growth of B. cinerea. Some aspects of structure-activity relationships are discussed.</description><subject>Biological and medical sciences</subject><subject>Botrytis cinerea</subject><subject>Chemical control</subject><subject>Control</subject><subject>fongicide</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fungal plant pathogens</subject><subject>fungicidas</subject><subject>fungicides</subject><subject>metabolite</subject><subject>metabolites</subject><subject>metabolitos</subject><subject>Phytopathology. Animal pests. Plant and forest protection</subject><subject>sesquiterpenoide</subject><subject>sesquiterpenoids</subject><subject>sesquiterpenos</subject><issn>0098-0331</issn><issn>1573-1561</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><recordid>eNp9kUtLxDAUhYMoOj42_gCZhYgI1Zt3s9TBUWHAxejGTUnbdIx02jFphf577-A47lyEkJMvh3NPCDmlcE0B9M3dFBhwRY3eISMqNU-oVHSXjABMmgDn9IAcxvgBAEylcp8cMMEETbkekbf50HTvLvo4tk2Jq_NV3yxsPbZF5798N4zbCmVbt4vexfWhsV0fbF3jTVH0IfhmMc7bLgylx2er4FCMbYjHZK-ydXQnm_2IvE7vXyaPyez54WlyO0sKrtIuwdwpV5IyIawywlnIS4wnJaWVrIw2JRVMa64ZKmXORQ5GCCloDpoLkfMjcvHjuwrtJ2bssqWPhatr27i2jxlVirMUAMHL_0EhjVRSGIbo1Q9ahDbG4KpsFfzShiGjkK1Lz_5KR_hs49vnS1du0d-WETjfADYWtq6CbQoftxzH2QSWsPWpbJvZRUDkdU6NUfiP2Azn3-HukGc</recordid><startdate>19941001</startdate><enddate>19941001</enddate><creator>COLLADO, I. G</creator><creator>ALEU, J</creator><creator>MACIAS-SANCHEZ, A. J</creator><creator>HERNANDEZ-GALAN, R</creator><general>Springer</general><scope>FBQ</scope><scope>IQODW</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SN</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope></search><sort><creationdate>19941001</creationdate><title>Synthesis and antifungal activity of analogues of naturally occurring botrydial precursors</title><author>COLLADO, I. G ; ALEU, J ; MACIAS-SANCHEZ, A. J ; HERNANDEZ-GALAN, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c368t-61983651244a694ea0bd4245511f5f979d14277372511db34b0944541b07344b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Biological and medical sciences</topic><topic>Botrytis cinerea</topic><topic>Chemical control</topic><topic>Control</topic><topic>fongicide</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fungal plant pathogens</topic><topic>fungicidas</topic><topic>fungicides</topic><topic>metabolite</topic><topic>metabolites</topic><topic>metabolitos</topic><topic>Phytopathology. Animal pests. Plant and forest protection</topic><topic>sesquiterpenoide</topic><topic>sesquiterpenoids</topic><topic>sesquiterpenos</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>COLLADO, I. G</creatorcontrib><creatorcontrib>ALEU, J</creatorcontrib><creatorcontrib>MACIAS-SANCHEZ, A. J</creatorcontrib><creatorcontrib>HERNANDEZ-GALAN, R</creatorcontrib><creatorcontrib>Universidad de Cadiz, Cadiz, Spain</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Ecology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of chemical ecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>COLLADO, I. G</au><au>ALEU, J</au><au>MACIAS-SANCHEZ, A. J</au><au>HERNANDEZ-GALAN, R</au><aucorp>Universidad de Cadiz, Cadiz, Spain</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis and antifungal activity of analogues of naturally occurring botrydial precursors</atitle><jtitle>Journal of chemical ecology</jtitle><addtitle>J Chem Ecol</addtitle><date>1994-10-01</date><risdate>1994</risdate><volume>20</volume><issue>10</issue><spage>2631</spage><epage>2644</epage><pages>2631-2644</pages><issn>0098-0331</issn><eissn>1573-1561</eissn><coden>JCECD8</coden><abstract>Analog compounds of the proposed intermediates of the biogenetic pathway to botrydial have been synthesized. These compounds were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea. Our results showed a fungistatic effect of some compounds on mycelium growth. The most significant effect was exerted by 2-alpha-hydroxy-2,3-dihydro-1-epiprobotrydial, which inhibited growth of B. cinerea. Some aspects of structure-activity relationships are discussed.</abstract><cop>New York, NY</cop><pub>Springer</pub><pmid>24241837</pmid><doi>10.1007/BF02036197</doi><tpages>14</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0098-0331 |
| ispartof | Journal of chemical ecology, 1994-10, Vol.20 (10), p.2631-2644 |
| issn | 0098-0331 1573-1561 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_16632800 |
| source | SpringerLink Journals - AutoHoldings |
| subjects | Biological and medical sciences Botrytis cinerea Chemical control Control fongicide Fundamental and applied biological sciences. Psychology Fungal plant pathogens fungicidas fungicides metabolite metabolites metabolitos Phytopathology. Animal pests. Plant and forest protection sesquiterpenoide sesquiterpenoids sesquiterpenos |
| title | Synthesis and antifungal activity of analogues of naturally occurring botrydial precursors |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T16%3A37%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Synthesis%20and%20antifungal%20activity%20of%20analogues%20of%20naturally%20occurring%20botrydial%20precursors&rft.jtitle=Journal%20of%20chemical%20ecology&rft.au=COLLADO,%20I.%20G&rft.aucorp=Universidad%20de%20Cadiz,%20Cadiz,%20Spain&rft.date=1994-10-01&rft.volume=20&rft.issue=10&rft.spage=2631&rft.epage=2644&rft.pages=2631-2644&rft.issn=0098-0331&rft.eissn=1573-1561&rft.coden=JCECD8&rft_id=info:doi/10.1007/BF02036197&rft_dat=%3Cproquest_cross%3E1459565492%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1459565492&rft_id=info:pmid/24241837&rfr_iscdi=true |