Synthesis and antifungal activity of analogues of naturally occurring botrydial precursors

Analog compounds of the proposed intermediates of the biogenetic pathway to botrydial have been synthesized. These compounds were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea. Our results showed a fungistatic effect of some compounds on mycelium growth. T...

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Veröffentlicht in:	Journal of chemical ecology 1994-10, Vol.20 (10), p.2631-2644
Hauptverfasser:	COLLADO, I. G, ALEU, J, MACIAS-SANCHEZ, A. J, HERNANDEZ-GALAN, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Botrytis cinerea Chemical control Control fongicide Fundamental and applied biological sciences. Psychology Fungal plant pathogens fungicidas fungicides metabolite metabolites metabolitos Phytopathology. Animal pests. Plant and forest protection sesquiterpenoide sesquiterpenoids sesquiterpenos
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Beschreibung
Zusammenfassung:	Analog compounds of the proposed intermediates of the biogenetic pathway to botrydial have been synthesized. These compounds were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea. Our results showed a fungistatic effect of some compounds on mycelium growth. The most significant effect was exerted by 2-alpha-hydroxy-2,3-dihydro-1-epiprobotrydial, which inhibited growth of B. cinerea. Some aspects of structure-activity relationships are discussed.
ISSN:	0098-0331 1573-1561
DOI:	10.1007/BF02036197