Evaluation of potential mutagenic effect of the liquid smoke preparation UTP in vivo: cytogenetic analysis of mouse bone marrow

Evaluation of potential mutagenic effect of the liquid smoke preparation UTP in vivo: cytogenetic analysis of mouse bone marrow

The effect of the liquid smoke preparation (UTP) on chromosomes of mouse bone marrow cells was evaluated by cytogenetic analysis. UTP Was administered to male and female mice in four concentrations: 100, 10, 1 and 0.1 ml UTP/1000 ml of drinking water continuously during 4 weeks ad libitum. The UTP c...

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Veröffentlicht in:Mutation research 1994, Vol.323 (1), p.89-92
Hauptverfasser: KAZIMIROVA, A, JABLONICKA, A
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological and medical sciences
Body Weight - drug effects
Bone marrow
Bone Marrow - drug effects
Bone Marrow Cells
Chemical mutagenesis
Chromosome aberrations
Cytogenetic analysis
Female
Flavoring Agents - toxicity
Liquid smoke preparation
Male
Medical sciences
Mice
Mice, Inbred ICR
Mutagenicity Tests
Mutagens - toxicity
Phenols - toxicity
Smoke
Toxicology
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Zusammenfassung:The effect of the liquid smoke preparation (UTP) on chromosomes of mouse bone marrow cells was evaluated by cytogenetic analysis. UTP Was administered to male and female mice in four concentrations: 100, 10, 1 and 0.1 ml UTP/1000 ml of drinking water continuously during 4 weeks ad libitum. The UTP concentrations used did not show any mutagenic effect during these testing conditions.
ISSN:0165-7992
0027-5107
DOI:10.1016/0165-7992(94)90050-7