The association of blood eosinophil counts to future asthma exacerbations in children with persistent asthma

The association of blood eosinophil counts to future asthma exacerbations in children with persistent asthma

Other variables selected in the final rate and risk models at the 300/mm3 eosinophil cutoff point that were associated with an increase in asthma exacerbations were (1) a history of asthma exacerbations in 2010 (P < .001 for both ratios), (2) decreasing age (P = .01 for both ratios), (3) GINA ste...

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Veröffentlicht in:The journal of allergy and clinical immunology in practice (Cambridge, MA) MA), 2015-03, Vol.3 (2), p.283-287.e4
Hauptverfasser: Zeiger, Robert S., MD, PhD, Schatz, Michael, MD, MS, Li, Qiaowu, MS, Chen, Wansu, MS, Khatry, Deepak B., PhD, Gossage, David, MBA, MD, Tran, Trung N., MD, PhD
Format: Artikel
Sprache:eng
Schlagworte:
Age
Allergy and Immunology
Asthma - blood
Asthma - epidemiology
Asthma - immunology
Blood
Body mass index
California - epidemiology
Child
Child, Preschool
Chronic Disease
Drug therapy
Eosinophils
Ethnicity
Female
Humans
Internal Medicine
Leukocyte Count
Male
Prognosis
Ratios
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Zusammenfassung:Other variables selected in the final rate and risk models at the 300/mm3 eosinophil cutoff point that were associated with an increase in asthma exacerbations were (1) a history of asthma exacerbations in 2010 (P < .001 for both ratios), (2) decreasing age (P = .01 for both ratios), (3) GINA step-care levels 4 and 5 versus step-care levels 1 and 2 (P = .04 for rate ratio), (4) 7 or more SABA canisters dispensed (P = .05 for rate ratio), (5) Asian versus non-Hispanic white ethnicity (P = .03 for both ratios), and (6) Hispanic versus non-Hispanic white ethnicity (P = .03 for risk ratio) (see Table E2 in this article's Online Repository at www.jaci-inpractice.org).\n4) 406 (16.6) =9 controller equivalent canisters dispensed§ 90 (27.0) 598 (28.2) 688 (28.1) .65 >=7 SABA canisters dispensed 59 (17.7) 444 (21.0) 503 (20.5) .17 Number of asthma exacerbations, mean ± SD 1.1 ± 1.2 0.7 ± 1.0 0.8 ± 1.1
ISSN:2213-2198
2213-2201
DOI:10.1016/j.jaip.2014.10.009