High blood eosinophil counts predict sputum eosinophilia in patients with severe asthma

[...]we have shown that using a cutoff of 0.45 x 109 cells/L for blood eosinophilia can usefully predict airway eosinophilia in patients with severe asthma receiving high levels of treatment.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of allergy and clinical immunology 2015-03, Vol.135 (3), p.822-824.e2
Hauptverfasser:	Fowler, Stephen J., MD, Tavernier, Gaël, PhD, Niven, Robert, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Anti-Asthmatic Agents - therapeutic use Asthma Asthma - diagnosis Asthma - drug therapy Asthma - immunology Asthma - pathology Beclomethasone - therapeutic use Biomarkers Blood Eosinophilia - diagnosis Eosinophilia - drug therapy Eosinophilia - immunology Eosinophilia - pathology Eosinophils - drug effects Eosinophils - immunology Eosinophils - pathology Humans Leukocyte Count Predictive Value of Tests Prednisone - therapeutic use Severity of Illness Index Sputum - cytology Studies Th2 Cells - drug effects Th2 Cells - immunology Th2 Cells - pathology Triamcinolone - therapeutic use
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Beschreibung
Zusammenfassung:	[...]we have shown that using a cutoff of 0.45 x 109 cells/L for blood eosinophilia can usefully predict airway eosinophilia in patients with severe asthma receiving high levels of treatment.
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2014.09.034