Radiotherapy after ovarian transposition: Ovarian function and fertility preservation

The outcome of ovarian function preservation and fertility after ovarian transposition was examined in women treated for cancer. Of 134 patients, 126 were treated with radiotherapy and 72 with chemotherapy. In a multivariate analysis, three factors appeared to be prognostic of ovarian castration: th...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 1993-02, Vol.25 (3), p.419-424
Hauptverfasser:	Haie-Meder, C., Mlika-Cabanne, N., Michel, G., Briot, E., Gerbaulet, A., Lhomme, C., Cosset, J.M., Sarrazin, D., Flamant, F., Hayatu, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Chemotherapy Drug-Related Side Effects and Adverse Reactions Female Fertility - physiology Genital system. Mammary gland Humans Medical sciences Neoplasms - drug therapy Neoplasms - radiotherapy Ovarian transposition Ovary - drug effects Ovary - radiation effects Ovary - surgery Radiotherapy Radiotherapy - adverse effects Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Retrospective Studies
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Zusammenfassung:	The outcome of ovarian function preservation and fertility after ovarian transposition was examined in women treated for cancer. Of 134 patients, 126 were treated with radiotherapy and 72 with chemotherapy. In a multivariate analysis, three factors appeared to be prognostic of ovarian castration: the age over 25, MOPP chemotherapy and a total dose to the ovaries higher than 5 Gy. The incidence of birth was lower than in the general population but no abnormality was observed.
ISSN:	0360-3016 1879-355X
DOI:	10.1016/0360-3016(93)90062-Z