Use of Proton Pump Inhibitors Is Associated With Anemia in Cardiovascular Outpatients

Background:Proton pump inhibitors (PPI) are frequently prescribed in combination with aspirin for preventing peptic ulcer in patients with atherosclerotic diseases. In contrast, long-term use of PPI has been suggested to be associated with iron or vitamin B12deficiency. The effect of PPI on hemoglob...

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Veröffentlicht in:	Circulation Journal 2014/12/25, Vol.79(1), pp.193-200
Hauptverfasser:	Shikata, Toshiyuki, Sasaki, Naoko, Ueda, Masahiro, Kimura, Takeshi, Itohara, Kanako, Sugahara, Masataka, Fukui, Miho, Manabe, Eri, Masuyama, Tohru, Tsujino, Takeshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anemia Anemia - blood Anemia - chemically induced Anemia - etiology Blood Cell Count Body Mass Index Cardiovascular disease Cardiovascular Diseases - blood Cardiovascular Diseases - epidemiology Creatinine - blood Diabetes Mellitus - epidemiology Erythrocyte Indices Female Hemoglobin Hemoglobins - analysis Humans Hyperlipidemias - epidemiology Hyperuricemia - epidemiology Iron - deficiency Kidney Diseases - blood Kidney Diseases - epidemiology Male Outpatients - statistics & numerical data Peptic Ulcer Hemorrhage - epidemiology Peptic Ulcer Hemorrhage - prevention & control Peripheral Arterial Disease - blood Peripheral Arterial Disease - epidemiology Polypharmacy Proton pump inhibitor Proton Pump Inhibitors - adverse effects Proton Pump Inhibitors - pharmacology Proton Pump Inhibitors - therapeutic use Retrospective Studies Risk Factors Vitamin B Deficiency - blood Vitamin B Deficiency - chemically induced
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