Alteration of the protein composition of bothrops jararaca venom and venom gland by isoproterenol treatment

1. 1. The protein composition of Bothrops jararaca venom and venom gland was analyzed through SDS-PAGE, after isoproterenol (IPR) treatment. 2. 2. Some proteins (47, 48, 57 and 72 kDa) were detected in the gland homogenate from the control but not from the IPR-treated samples. 3. 3. Three proteins (...

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Veröffentlicht in:	International journal of biochemistry 1993, Vol.25 (10), p.1491-1496
Hauptverfasser:	B., Gabriel, Burgos, Nunez, Gonçalves, Luis R.C., Furtado, M.Fátima D., Fernandes, Wilson, Nicolau, José
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bothrops jararaca Fundamental and applied biological sciences. Psychology Mouth. Exocrine and endocrine salivary glands. Teeth. Esophagus Vertebrates: digestive system
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Zusammenfassung:	1. 1. The protein composition of Bothrops jararaca venom and venom gland was analyzed through SDS-PAGE, after isoproterenol (IPR) treatment. 2. 2. Some proteins (47, 48, 57 and 72 kDa) were detected in the gland homogenate from the control but not from the IPR-treated samples. 3. 3. Three proteins (26.5, 44.5 and 53 kDa) were detected in the venom gland from IPR-treated snakes but not from the venom gland from the control. 4. 4. In the venom samples proteins of 41 and 74 kDa were detected only in the IPR treated samples, while proteins of 17 and 28 kDa were detected only in the control. 5. 5. The biological activity of the venom did not change with IPR treatment.
ISSN:	0020-711X
DOI:	10.1016/0020-711X(93)90695-B