Olopatadine, a non-sedating H1 antihistamine, decreases the nocturnal scratching without affecting sleep quality in atopic dermatitis

Olopatadine, a non-sedating H1 antihistamine, decreases the nocturnal scratching without affecting sleep quality in atopic dermatitis

We have demonstrated for the first time that a second‐generation antihistamine ameliorates nocturnal scratching behavior in atopic dermatitis patients using a modified wristwatch‐type acoustic scratching counting system that we have recently developed. We also analyzed the sleep quality by simultane...

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Veröffentlicht in:Experimental dermatology 2015-03, Vol.24 (3), p.227-229
Hauptverfasser: Yamanaka, Keiichi, Motomura, Eishi, Noro, Yuichi, Umeda, Koji, Morikawa, Takuya, Umeda-Togami, Kumi, Omoto, Youichi, Isoda, Kenichi, Kondo, Makoto, Tsuda, Kenshiro, Okuda, Masahiro, Gabazza, Esteban C., Mizutani, Hitoshi
Format: Artikel
Sprache:eng
Schlagworte:
antihistamine
atopic dermatitis
Dermatitis, Atopic - complications
Double-Blind Method
electroencephalogram
Electroencephalography
Histamine H1 Antagonists, Non-Sedating - therapeutic use
Humans
Olopatadine Hydrochloride - therapeutic use
Pruritus - drug therapy
Pruritus - etiology
scratching
Severity of Illness Index
sleep quality
Sleep Stages - physiology
Time Factors
Visual Analog Scale
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Zusammenfassung:We have demonstrated for the first time that a second‐generation antihistamine ameliorates nocturnal scratching behavior in atopic dermatitis patients using a modified wristwatch‐type acoustic scratching counting system that we have recently developed. We also analyzed the sleep quality by simultaneous recording of electroencephalogram, and found that sleep quality was unaffected.
ISSN:0906-6705
1600-0625
DOI:10.1111/exd.12630