del Nido versus Buckberg cardioplegia in adult isolated valve surgery

Background del Nido solution is a non–glucose-based, single-dose cardioplegic solution with few data supporting its safety in adults. We hypothesized that it and Buckberg solution offer myocardial protection of equivalent safety for isolated adult valve surgery. Methods Adult patients undergoing primary isolated aortic or mitral valve surgery with del Nido or Buckberg solution from January 2010 to September 2013 were 1:1 propensity matched (85 aortic valve, 110 mitral valve), and outcomes were compared. Results After aortic valve operations, no hospital deaths occurred, and troponin T levels (median 0.19 ng · mL−1 for del Nido vs 0.21 ng · mL−1 for Buckberg) were similar, with no statistically significant change in left ventricular ejection fraction ( P = .4). Aortic clamp, bypass, and operating room times were shorter with del Nido solution (44 ± 14 vs 56 ± 19; 56 ± 18 vs 70 ± 24; and 285 ± 44 vs 308 ± 61 minutes, respectively; P